Journal of Yeungnam Medical Science

Yoon Ki Park

8 Articles

The Effect of Probiotic on Constipation in Rats.: Jin Hee Kim, Sung Chul Park, Jong Yeon Kim, Yoon Ki Park; Yeungnam Univ J Med. 2009;26(2):102-107. Published online December 31, 2009; DOI: https://doi.org/10.12701/yujm.2009.26.2.102

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Abstract PDF: BACKGROUND
Constipation is one of the most common disorders in Korea and Western countries. It may be related with life style, diet, physical activity, age, stress and gender, and particularly premenopausal women experience constipation more often than men due to the significant prolongation of the mean colonic transit in women. The aim of this study was to evaluate the effect of a probiotic on constipation in loperamide-induced constipated rats. MATERIALS AND METHODS: The rats were divided into 3 groups. Constipation was induced by administration of loperamide for 5 days, and the excreted amount as well as the number of feces was observed. Lactic acid bacteria as a probiotic were administered orally every day for 5 days. RESULTS: The results showed that loperamide administration induced severe experimental constipation in rats. The amount of feces was decreased and the number of pellets was increased by loperamide. The water content in the feces as a parameter of constipation was also decreased by loperamide. On the other hand, the dry weights of feces were not significantly different among the groups. It represents that the amount of food consumption might have been similar among the groups, and constipation was caused by delayed intestinal movement. CONCLUSION: Probiotic administration for 5 days in rats partly alleviated or prevented the constipation induced by loperamide.

A Case of Leiomyoma of The Lateral Vaginal Wall.: Sung Chul Park, Doo Jin Lee, Sung Ho Lee, Yoon Ki Park; Yeungnam Univ J Med. 2008;25(2):124-127. Published online December 31, 2008; DOI: https://doi.org/10.12701/yujm.2008.25.2.124

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Abstract PDF: Leiomyomas are common in the myometrial layer of the uterus, though they are rarely found in other reproductive organs. Leiomyomas are benign, hormone-sensitive smooth muscle tumors. They develop during the reproductive years and regress after menopause. Preoperative diagnosis is difficult to make. We present a case of a 54-year-old woman with a vaginal wall tumor. The management in this case included surgical excision. Histologic examination definitively confirmed the diagnosis of a vaginal leiomyoma. We report the details of this case along with a brief review of the literature.

A Case of Uterine Didelphys with Obstructed Hemivagina and Ipsilateral Renal Agenesis: Sung Chul Park, Doo Jin Lee, Sung Ho Lee, Yoon Ki Park; Yeungnam Univ J Med. 2007;24(2 Suppl):S737-741. Published online December 31, 2007; DOI: https://doi.org/10.12701/yujm.2007.24.2S.S737

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Abstract PDF

Frequency of female genital congenital abnormality is about 0.2%. We suspect female as uterine abnormality with hematocolpos, who after menarche with progressive abdominal pain during menses, in associated with the finding of growing pelvic mass and not visible unilateral kidney at urography. Commonly it was fined with acute lower abdominal pain at puberty. Early diagnosis is very important to treatment and to fertility of patient. The simple and adequate treatment of the condition is incision of the obstructed vaginal septum providing adequate drainage of the retained blood. If diagnosis of this disease is late, it may occur complications of hematocolpos, hematosalphinx, endometriosis and pelvic adhesions by flowing backward of mensturational blood. Also it may cause decreasing fertility and secondary infection. We report a case of uterine didelphys with obstructed hemivagina and ipsilateral renal agenesis with a brief review of the literature.

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A Case Report on Secondary Dysmenorrhea with Herlyn-Werner-Wunderlich Syndrome
Pyung-Wha Kim, Ji-Yeong Im, Yong-Tae Jeon, Eun-Hee Lee
The Journal of Oriental Obstetrics and Gynecology.2016; 29(4): 69. CrossRef

A Case of Spontaneous Uterine Rupture of the Unscarred Uterus in 14 Weeks Gestation.: Jeong Suk Kim, Jin Hee Kim, Yeun Kyoung Bae, Yoon Ki Park; Yeungnam Univ J Med. 2004;21(2):251-255. Published online December 31, 2004; DOI: https://doi.org/10.12701/yujm.2004.21.2.251

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Abstract PDF: Spontaneous uterine rupture of the unscarred uterus during the second trimester of pregnancy is rare, but it is a surgical emergency. Because it results in rapid deterioration of patient and high mortality despite of prompt operation and massive transfusion, early diagnosis and proper management are critical for optimizing patient care. We present a case of spontaneous uterine rupture with fetal death in 14 weeks gestation with a brief review of literatures.

The Production Mechanism of TNF-alpha and IL-6 by Group IIA Phospholipase A2.: Jae Hong Ahn, Dae Won Park, Jin Hee Kim, Jei Jun Bae, Yeun Kyoung Bae, Yoon Ki Park; Yeungnam Univ J Med. 2004;21(2):177-190. Published online December 31, 2004; DOI: https://doi.org/10.12701/yujm.2004.21.2.177

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Abstract PDF: BACKGROUND
Secretory phospholipase A2 (sPLA2) are a group of extracellular enzymes that release fatty acids at the sn-2 position of phospholipids. Group IIA sPLA2 (sPLA2-IIA) has been detected in the inflammatory fluids, and its plasma level increases in the inflammatory disease. This study examined the effect of sPLA2-IIA on mouse macropahges in order to investigate the potential mechanism of sPLA2-induced inflammation. MATERIALS AND METHODS: Wild type PLA2 and mutant H48Q PLA2 were purified from HEK293 cells transfected with the corresponding plasmids, and the PLA2 activities were measured using 1-palmitoyl-2-[1- (14) C]linoleoyl-3-phosphatidylethanolamine as substrates. The TNF-alpha and IL-6 released in the supernatants were determined by ELISA. In addition, the TNF-alpha and IL-6 mRNA were analyzed by RT-PCR. RESULTS: sPLA2-IIA stimulated the production of TNF-alpha and IL-6 in a dose- and time-dependent manner. In addition, the effect of sPLA2-IIA on cytokine production from the macrophage was found to be associated with the accumulation of their specific mRNA. The mRNA levels of TNF-alpha and IL-6 peaked at 2 and 6 hours in a time-dependent manner, respectively. CONCLUSION: In conclusion, the production of proinflammatory cytokine might be mediated by the binding of sPLA2-IIA to the receptors.

Three cases of symphysis pubis separation associated with delivery.: Jae Hong Ahn, Young Jin Jang, Dong Hyuk Lee, Young Gi Lee, Yoon Ki Park; Yeungnam Univ J Med. 2000;17(1):93-98. Published online June 30, 2000; DOI: https://doi.org/10.12701/yujm.2000.17.1.93

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Abstract PDF: Symphysis pubis separation is an uncommon but not rare complication of delivery. Characteristic symptoms of symphyseal separation include suprapubic pain and tenderness which radiate to the back or legs, difficult ambulation, and bladder dysfunction. Clinical history, presenting symptoms, and response to therapy are sufficient to make the diagnosis, although radiographic documentation of symphyseal separation by x-ray or ultrasound are frequently used to confirm the diagnosis. The underlying etiology of symptomatic symphyseal separation has not been fully elucidated. Associations with macrosomia, pathological joint loosening, and increased force placed on the pelvic ring have been suggested as possible etiologies. Conservative therapy, including bed rest, pelvic binders, ambulation devices, and mild analgesics usually result in complete recovery within 4-16 weeks. Our experience of three cases of peripartum symphysis pubis separation delivered from 1998 to 1999 were reviewed with related articles.

Maternal Weight Gain Pattern and Birth Weight.: Mok Jin Kim, Ho Yeol Lee, Young Gi Lee, Yoon Ki Park, Doo Jin Lee, Sung Ho Lee; Yeungnam Univ J Med. 1998;15(1):135-142. Published online June 30, 1998; DOI: https://doi.org/10.12701/yujm.1998.15.1.135

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Maternal weight gain during pregnancy has been consistently associated with infant birth weight and pregnancy outcome. Our purpose was to determined the relationship between maternal weight gain pattern and birth weight. Consequently, maternal weight gain is monitored carefully and is encouraged during prenatal care in order to improve pregnancy outcome. Our study group included both 424 uncomplicated women and infant delivered at the Yeungnam University Hospital between 1993-1996. All recorded prenatal weight gain measurements were used to estimate maternal trimester weight gain, pattern of gain (based on low versus not-low gain at each trimester), and total gain at delivery. Multiple linear regression analysis was used to assess the relationship between these weight gain measurements and fetal birth weight. Each kilogram of maternal gain in the first, second, and third trimesters was associatedwith statistically related to the increase in fatal birth weight by 31.3, 19.0, and 24.5g, respectively. When compaired with the pattern of gain that was not low in any trimester, patterns with low gain in the first trimesters were associated with significant decreases in birth weight, but no important change in birth weight was seen for the group whose gains were not low in the first trimester. The results suggest that specific patterns of maternal weight gain, particularly weight gain during the first trimester, are related to fetal birth weight.

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Effects of Yoga during Pregnancy on Weight Gain, Delivery Experience and Infant's Birth Weight
Eun Sun Ji, Kyoul Ja Cho, Hyun Jeong Kwon
Korean Journal of Women Health Nursing.2009; 15(2): 121. CrossRef

Diagnostic Value of Serum Beta-hCG Measured by EIA in Suspected Ectopic Pregnancy.: Yoon Ki Park, Jong Wook Kim, Tae Hyung Lee, Wan Seok Park, Sung Ho Lee, Wun Yong Chung; Yeungnam Univ J Med. 1985;2(1):221-227. Published online December 31, 1985; DOI: https://doi.org/10.12701/yujm.1985.2.1.221

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Abstract PDF: Thirty-four patients with suspected ectopic pregnancy whose serum hCG levels had been measured by beta-hCG EIA before surgery were evaluated retrospectively. The results were as follows: 1. Final diagnosis of thirty- four patients with suspected ectopic pregnancy comprised twenty-eight tubal pregnancy, five ruptures of hemorrhagic corpus luteum and one tubo-ovarian abscess. One of the five patients with rupture of hemorrhagic corpus luteum was accompanied by missed abortion. 2. Range of serum hCG levels in twenty-eight patients with tubal pregnancy was 59-21, 980 mIU/ml and that of four patients with rupture of hemorrhagic corpus luteum and one patient with tubo-ovarian abscess was 0.6-6.6 mIU/ml. Serum hCG level of a patient with rupture of hemorrhagic corpus luteum who was accompanied by missed abostion was 200 mIU/ml. 3. Serum hCG levels in twenty-two of twenty-eight patients with tubal pregnancy were lower than 3,000 mIU/ml. Low serum hCG level below 100 mIU/ml and high serum hCG levl above 6,500 mIU/ml were noticed in four and six patients with tubal pregnancy recpectively. 4. Mean serum hCG levels (±SD) of twelve patients with tubal pregnancy who had intraabdominal free blood of less than 500ml and sixteen patients with tubal pregnancy who had intraabdominal free blood of more than 500ml were 4,131 (±7,801) mIU/ml and 3,208 (±5,081) mIU/ml, respectively. There was no statistical difference in the mean level of serum hCG between both group (P>0.05). 5. Mean serum hCG levels (±SD) of thirteen patients with unruptured tubal pregnancy and fifteen patients with ruptured tubal pregnancy were 2,628 (±5,448) mIU/ml and 4,449 (±6,938) mIU/ml, respectively. Mean level of serum hCG was statistically higher in ruptured tubal pregnancy (P<0.01). 6. Positive rate of urine pregnancy test in the diagnosis of ectopic pregnancy was 64% (16/25) and mean range of serum hCG level of nine patients with false negative result were 353 mIU/ml and 59933 mIU/ml.

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